ABSTRACT
Objective@#To assess the clinical effects of transurethral holmium laser enucleation of the prostate (HoLEP) combined with Jisheng Shenqi Decoction (HoLEP + JSSD) on BPH.@*METHODS@#This study included 110 BPH patients treated in our hospital from August 2017 to April 2018, who were randomly assigned to receive HoLEP (n = 55) or HoLEP + JSSD (n = 55). We compared the pre- and post-operative IPSS, quality of life (QOL) score, prostate volume, postvoid residual urine volume (PVR), maximum urinary flow rate (Qmax), average urinary flow rate (Qavg) and levels of serum T, E2 and T/E2 as well as postoperative complications between the two groups of patients.@*RESULTS@#After treatment, both IPSS and QOL score were significantly lower in the HoLEP + JSSD than in the HoLEP group (P 0.05) or the total incidence rate of complications postoperatively (21.82% vs 29.09%, P > 0.05).@*CONCLUSIONS@#HoLEP + JSSD can significantly alleviate the lower urinary tract symptoms as well as improve the QOL and bladder and urinary tract functions of BPH patients.
ABSTRACT
OBJECTIVE: To investigate and evaluate the antacid property of alkaline montmorillonite. METHODS: Parameters of the antacid, such as active component content, solubility, and granularity, were determined. The antacid was characterized by BET, XRD, and SEM, and evaluated by acute toxicity test, acid resistance in vitro experiment, and gastric mucosa protection experiment. RESULTS: The content and solubility of the active component Ca(OH)2 were 37% and 84 mg · L-1, respectively, which showed that Ca(OH)2 was relatively firmly loaded and the alkalinity was largely decreased. The granularity and specific area were 8.3 μm and 37.5 m · g-1, respectively, which were beneficial to gastric acid adsorption and gastric mucosa protection. Besides, XRD characterization results revealed the antacid retained a structure of montmorillonite. And SEM patterns indicated the surface of the antacid was relatively smooth, which was conducive to gastric mucosa protection. In addition, the results of acute toxicity test, acid resistance in vitro experiment, and gastric mucosa protection experiment demonstrated that the antacid was safe and non-toxic. Meanwhile, it pocessed excellent properties of acid resistance and gastric mucosa protection. CONCLUSION: Alkaline montmorillonite antacid is an excellent antacid and gastric mucosa protectant.